Key result
Aerobic exercise training boosts peak systolic middle cerebral blood flow velocity ~6% in healthy postmenopausal women.
Why the study?
The effect of aerobic exercise training on age-related reduction in cerebral blood flow in postmenopausal women was unclear.
Does moderate aerobic exercise training improve middle cerebral blood flow velocity and cerebrovascular resistance in healthy postmenopausal women?
Does moderate aerobic exercise training improve middle cerebral blood flow velocity and cerebrovascular resistance in healthy postmenopausal women?
Absolute Event Rate: 99% vs 93%
p-value: p=<0.05
An 8-week moderate aerobic exercise program significantly improves cerebral hemodynamics in healthy postmenopausal women, suggesting a potential non-pharmacological strategy to attenuate age-related cerebral blood flow decline.
May support aerobic exercise to improve cerebral hemodynamics in postmenopausal women; leaves open confirmation in randomized outcome trials.
Background: Age-related decrease in cerebral blood flow is a risk factor for cognitive decline.Aerobic exercise training improves vascular and cognitive functions.However, the effect of exercise training on age-related reduction in cerebral blood flow is unclear.The present study investigated whether aerobic exercise training can increase cerebral blood flow in postmenopausal women.Methods: Twenty healthy postmenopausal women were assigned to either the exercise training group (n Z 10) or the control group (n Z 10).The exercise group completed 8 weeks of moderate aerobic exercise intervention.The control group did not change their physical activity level.Before and after each intervention, middle cerebral blood flow velocity and cerebrovascular resistance were measured using transcranial Doppler ultrasonography.Results: The baseline middle cerebral blood flow velocity, cerebrovascular resistance, and most other key dependent variables did not significantly differ between the groups.Aerobic exercise training significantly increased middle cerebral blood flow velocity and significantly decreased cerebrovascular resistance, whereas no such changes were observed in the control group.Conclusions: We showed that aerobic exercise training increased middle cerebral blood flow velocity and decreased cerebrovascular resistance in postmenopausal women.The results of the current study suggest that regular aerobic exercise may attenuate aging-induced decrease in cerebral blood flow.
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Akazawa et al. (2012) studied Healthy postmenopausal women (n=20). Aerobic exercise training vs. No change in physical activity was evaluated on Peak systolic middle cerebral blood flow velocity (cm/s) (p=<0.05). Aerobic exercise training for 8 weeks significantly increased peak systolic middle cerebral blood flow velocity and decreased cerebrovascular resistance in healthy postmenopausal women.
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