Key result
Aggressive therapy with IVIG, steroids, and warfarin resolves rapid-onset infant Kawasaki coronary aneurysm.
Why the study?
Cardiac involvement in Kawasaki disease typically occurs in the second week, but timing may differ in young infants, requiring individualized diagnosis and treatment.
Case Report (n=1)
No
Highlights that cardiac complications in young infants with Kawasaki disease can develop earlier than the typical second week, necessitating individualized diagnostic and treatment approaches.
Early aneurysm risk in infantile Kawasaki disease may warrant prompt echocardiography; this case leaves open revised diagnostic timing criteria.
Background Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the second week of the disease. Case presentation: We describe the case of KD developing in a 3-month infant, with an early occurrence of coronary artery aneurism after only 3 days of fever, complicated by thrombosis, requiring aggressive treatments. Conclusions Time of development of cardiac complications can be different in young infants with KD and both diagnostic criteria and treatment indications should be individualized in this class of age.
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Jiao et al. (2023) conducted a case report in Kawasaki disease (n=1). IVIG, steroids, and warfarin was evaluated on Clinical and echocardiographic improvement. A 3-month-old infant with Kawasaki disease developed a coronary artery aneurysm after only 3 days of fever, which improved following treatment with IVIG, steroids, and warfarin.
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