Key result
Elderly patients (≥65 years) undergoing elective resection for stage I-II colon cancer had similar rates of postoperative complications compared to younger patients (64.2% vs 47.2%; p≥0.05).
Why the study?
Does elective surgical resection in elderly patients with stage I-II colon cancer result in higher short-term complications compared to younger patients?
Observational (n=103)
Does elective surgical resection in elderly patients with stage I-II colon cancer result in higher short-term complications compared to younger patients?
Absolute Event Rate: 64.2% vs 47.2%
p-value: p=≥0.05
Elderly patients undergoing elective resection for stage I-II colon cancer do not have a significantly increased risk of short-term complications compared to younger patients, despite higher ASA scores and polypharmacy.
Short-term outcomes may be comparable despite high comorbidity rates; leaves open whether age-specific risk models improve selection for elective resection.
AIM: The aim of this study was to analyze the influence of comorbidities and to compare the short-term results of elective surgical resection of stage I-II colon adenocarcinoma in elderly (≥65 years) versus younger patients. PATIENTS AND METHODS: Two groups of sex-matched younger and older patients were compared: Group A: N=36, median age 58 (range=43-65) years; and group B: N=67, median age 73 (range=66-86) years. RESULTS: Overall, 71 out of 103 (68.9%) patients had one or more comorbidities. A greater number of older patients had an American Society of Anesthesiologists (ASA) score >2 (p=0.004) and were on multiple medications (polypharmacy) (p=0.016), but the distribution of the other parameters was similar (p≥0.05). Intra- and postoperative complications in group A vs. B occurred in 25.0% vs. 26.9%, and 47.2% vs. 64.2%, respectively (p≥0.05). CONCLUSION: Elderly patients with colon cancer scheduled to elective surgical resection should not be considered at increased risk of intra- or short-term postoperative complications with respect to younger patients. However, they require careful individual preoperative evaluation because they are usually polypharmacy users and have a higher ASA score.
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Basso et al. (2017) conducted an observational in Stage I-II colon adenocarcinoma (n=103). Elderly age (≥65 years) vs. Younger age (<65 years) was evaluated on Postoperative complications (p=≥0.05). Elderly patients (≥65 years) undergoing elective resection for stage I-II colon cancer had similar rates of postoperative complications compared to younger patients (64.2% vs 47.2%; p≥0.05).
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