Key result
Older age (≥ 70 years) was not independently associated with systemic complications after colorectal cancer surgery after adjusting for clinical factors such as ASA score (p=0.36).
Why the study?
Does advanced age (≥70 years) independently increase the risk of postoperative complications in patients undergoing surgery for colorectal cancer?
Population
271 patients who underwent surgery for pathologically confirmed colorectal cancer at Aga Khan University…
Comparison
Colorectal cancer surgery in elderly patients vs Colorectal cancer surgery in younger patients
Design
Cohort
Follow-up
30 days
Authors
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Supports prioritizing ASA class over age for risk assessment; leaves open whether frailty measures improve prediction in colorectal cancer surgery.
Cohort (n=271)
No
Does advanced age (≥70 years) independently increase the risk of postoperative complications in patients undergoing surgery for colorectal cancer?
Odds Ratio: 0.73 (95% CI 0.32–1.66)
Absolute Event Rate: 28.6% vs 17.2%
p-value: p=0.36
Advanced age alone is not an independent predictor of postoperative complications after colorectal cancer surgery, suggesting patient selection should be based on clinical status and ASA class rather than age.
Khan et al. (2011) conducted a cohort in Colorectal cancer (n=271). Age ≥ 70 years vs. Age < 70 years was evaluated on Systemic complications (OR 0.73, 95% CI 0.32-1.66, p=0.36). Older age (≥ 70 years) was not independently associated with systemic complications after colorectal cancer surgery after adjusting for clinical factors such as ASA score (p=0.36).
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