December 1, 2003Cardiovascular Research
Tissue engineering of aortic heart valves
Key result
Tissue engineering of heart valves aims to generate completely biological, autologous living valves to overcome the limitations of current mechanical and biological prostheses.
Design
Editorial
Authors
Discussion
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Member takes
Implication
Tissue engineering approaches hold promise for generating biological, autologous living valves that may overcome limitations of current mechanical and biological prostheses.
PICO
P
Population
Advanced valvular heart disease
I
Intervention / Comparator
Tissue engineering of heart valves
Tissue engineering approaches hold promise for generating biological, autologous living valves that may overcome limitations of current mechanical and biological prostheses.
Limitations
- Pronounced thrombogenicity of currently employed polymers and biological matrix components
- Cell detachment under high pressure aortic flow conditions
Cite This Study
Wolfram‐Hubertus Zimmermann (2003) conducted an editorial in Advanced valvular heart disease. Tissue engineering of heart valves was evaluated. Tissue engineering of heart valves aims to generate completely biological, autologous living valves to overcome the limitations of current mechanical and biological prostheses.