Key result
Scrub typhus myocarditis occurs in ~12% of patients without significantly increasing mortality or hospital stay.
Why the study?
The spectrum of cardiac manifestations in scrub typhus infection and their relationship to clinical outcomes were not well characterized.
Population
81 patients admitted with scrub typhus infection, mean age 49.4 years, 35 males
Comparison
Patients with myocarditis versus those without myocarditis
Design
Observational cohort study
Authors
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Myocarditis may flag higher-risk scrub typhus; hypothesis-generating and requires prospective validation before changing practice.
Observational (n=81)
Odds Ratio: 1.17 (95% CI 0.98–1.4)
Cardiac manifestations, including myocardial injury and myocarditis, are frequent in severe scrub typhus infection and are associated with increased morbidity but not mortality.
Gunasekaran et al. (2018) conducted an observational in Scrub typhus infection (n=81). Myocarditis vs. Patients without myocarditis was evaluated on Longer hospital stay (OR 1.17, 95% CI 0.98-1.40). Myocarditis in scrub typhus infection was present in 12.3% of patients and was associated with a trend toward longer hospital stay (OR 1.17; 95% CI 0.98-1.40) but not increased mortality.
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