Key result
3D printed models successfully predicted coronary obstruction and annular rupture in an in vitro release process, consistent with actual intraoperative complications in 4 fatal TAVR cases.
Why the study?
Pre-procedural cardiac CT imaging for TAVR evaluation has imperfections that may fail to predict fatal complications during and after the operation.
Does 3D printed modeling improve the prediction of fatal complications in patients undergoing TAVR compared to standard CT imaging?
Observational (n=4)
Does 3D printed modeling improve the prediction of fatal complications in patients undergoing TAVR compared to standard CT imaging?
Patient-specific 3D printed models may accurately simulate intraoperative status and predict fatal complications like coronary obstruction and annular rupture during TAVR.
May support pre-TAVR risk stratification in select cases; hypothesis-generating and should not yet change practice.
INTRODUCTION: Transcatheter aortic valve replacement (TAVR) can have some fatal complications during and after the operation. Until recently, pre-procedural imaging with cardiac computed tomography (CT), which is required to evaluate for TAVR, had its own imperfections. We aimed to determine whether 3D printed models can predict complications when other pre-procedural imaging techniques failed. METHODS: Vascular center patients with aortic valve stenosis, who died after TAVR between June 2011 and June 2016, were enrolled in this retrospective study. The CT datasets of the patients were imported into a three-dimensional (3D) construction software and then printed by flexible material. To predict complications during and after operations, we designed a release test using the non-valved stent mode that was consistent with the Edwards Sapien XT valve in size and radial support force. RESULT: The 3D model predicted the coronary obstruction and annular rupture in the in vitro release process, which was consistent with what happened in the actual operation. CONCLUSION: Three-dimensional modeling facilitates pre-operative assessment of patients receiving TAVR, with accurate simulation of intraoperative status.
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Zhang et al. (2019) conducted an observational in Aortic valve stenosis (n=4). 3D printed models for pre-operative assessment was evaluated on Prediction of complications (coronary obstruction and annular rupture). 3D printed models successfully predicted coronary obstruction and annular rupture in an in vitro release process, consistent with actual intraoperative complications in 4 fatal TAVR cases.
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