Key result
HbA1c < 8% is linked to higher auc-PPG values versus poorly controlled diabetes.
Why the study?
Diabetes mellitus accelerates atherosclerosis, and non-invasive monitoring of arterial condition using PPG characteristics may aid in detecting abnormalities related to HbA1c levels.
Does HbA1c level correlate with arterial stiffness measured by auc-PPG in diabetic patients?
Observational
Does HbA1c level correlate with arterial stiffness measured by auc-PPG in diabetic patients?
Photoplethysmogram contour analysis (auc-PPG) can non-invasively detect differences in arterial stiffness associated with varying levels of glycemic control in diabetic patients.
Answers are grounded in this paper and cite their sources.
Auc-PPG may detect glycemic control-related stiffness differences in diabetes; leaves open causal links and clinical utility pending prospective validation.
Diabetes mellitus accelerates atherosclerosis. Monitoring arterial condition promises to be an advantage in the detection of any abnormalities. In this study, the characteristics of analysis by photoplethysmogram (PPG) were investigated non-invasively among diabetic patients. An area under the curve (auc-PPG) was compared for two levels of HbA1c, namely HbA1c < 8% (Group 1) and HbA1c > 10% (Group 2). Auc-PPG was found to be significantly higher among diabetic subjects with HbA1c<8% than among those with HbA1c > 10%. Further analysis was performed to investigate the effect of age on auc-PPG. The mean values of auc-PPG were still significantly higher among diabetic patients with HbA1c < 8% than among those with HbA1c > 10%. These results show that the auc-PPG method could be a parameter in determining the arterial stiffness in relation to the level of HbA1c.
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Usman et al. (2013) conducted an observational in Diabetes mellitus. HbA1c < 8% vs. HbA1c > 10% was evaluated on Area under the curve of photoplethysmogram (auc-PPG). Diabetic patients with HbA1c < 8% had significantly higher auc-PPG values compared to those with HbA1c > 10%.
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