Key result
HbA1c under 8% is linked to lower arterial stiffness versus HbA1c over 10% in diabetes.
Why the study?
Diabetes mellitus accelerates atherosclerosis and non-invasive monitoring of arterial condition may aid in detecting abnormalities related to glycemic control.
Does the level of HbA1c affect arterial stiffness as measured by the area under the curve of a photoplethysmogram (auc-PPG) in diabetic patients?
Cross-Sectional (n=101)
No
Does the level of HbA1c affect arterial stiffness as measured by the area under the curve of a photoplethysmogram (auc-PPG) in diabetic patients?
Photoplethysmogram contour analysis (auc-PPG) can non-invasively detect differences in arterial stiffness associated with varying levels of glycemic control in diabetic patients.
Answers are grounded in this paper and cite their sources.
Associated with lower arterial stiffness at better glycemic control; hypothesis-generating for auc-PPG, needs longitudinal validation before clinical use.
Diabetes mellitus accelerates atherosclerosis. Monitoring arterial condition promises to be an advantage in the detection of any abnormalities. In this study, the characteristics of analysis by photoplethysmogram (PPG) were investigated non-invasively among diabetic patients. An area under the curve (auc-PPG) was compared for two levels of HbA1c, namely HbA1c < 8% (Group 1) and HbA1c > 10% (Group 2). Auc-PPG was found to be significantly higher among diabetic subjects with HbA1c<8% than among those with HbA1c > 10%. Further analysis was performed to investigate the effect of age on auc-PPG. The mean values of auc-PPG were still significantly higher among diabetic patients with HbA1c < 8% than among those with HbA1c > 10%. These results show that the auc-PPG method could be a parameter in determining the arterial stiffness in relation to the level of HbA1c.
No takes yet. Share an insight, caveat, or question.
Usman et al. (2013) conducted a cross-sectional in Type 2 diabetes (n=101). HbA1c < 8% vs. HbA1c > 10% was evaluated on Area under the curve of photoplethysmogram (auc-PPG) (η² 0.111, p=<0.001). Diabetic patients with HbA1c < 8% had a higher area under the photoplethysmogram curve compared to those with HbA1c > 10%, indicating lower arterial stiffness.
Synapse has enriched 10 related papers. Consider them for comparative context: