Key result
Abnormal exercise ECG with normal stress echo evaluated for MACE risk in cohort study.
Why the study?
The clinical significance of abnormal exercise ECG with normal stress echocardiogram findings in assessing risk of major adverse cardiac events was unclear.
Cohort
Hypothesis-generating from Level 3 cohort data; leaves open whether findings warrant practice change or further RCTs.
Article| June 2021 SEE Question ASA Monitor June 2021, Vol. 85, 21. https://doi.org/10.1097/01.ASM.0000754224.33113.cd Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Search Site Citation SEE Question. ASA Monitor 2021; 85:21 doi: https://doi.org/10.1097/01.ASM.0000754224.33113.cd Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search nav search search input Search input auto suggest search filter All ContentAll PublicationsASA Monitor Search Advanced Search Topics: echocardiography, exercise stress test, stress echocardiography A recent observational cohort study compared the annualized rate of major adverse cardiac events (MACE) in patients with abnormal exercise electrocardiograms (+ECG) but normal stress echocardiograms (–Echo) to patients with normal exercise ECGs (–ECG) and normal stress echocardiograms (–Echo). According to this study, which of the following statements is MOST likely true of the annualized MACE event rate in the +ECG/–Echo group compared with the –ECG/–Echo group? Both exercise ECG and stress Echo are used in clinical practice to evaluate patients at risk for coronary artery disease (CAD). The absence of regional wall motion abnormalities with stress (negative stress Echo) portends a low risk of CAD. Conversely, a stress Echo that reveals regional wall motion abnormalities has been correlated with an increased risk of CAD. At times, patients will undergo exercise ECG before or in addition to stress Echo, and a fraction of patients will demonstrate ischemic ST segment changes... You do not currently have access to this content.
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A 2021 study conducted a cohort in Coronary artery disease risk. Abnormal exercise electrocardiogram (+ECG) with normal stress echocardiogram (-Echo) vs. Normal exercise electrocardiogram (-ECG) with normal stress echocardiogram (-Echo) was evaluated on Annualized rate of major adverse cardiac events (MACE). The abstract presents a clinical question comparing MACE rates in patients with abnormal versus normal exercise ECGs and normal stress echocardiograms, without providing the study results.
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