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September 29, 2026Circulation

American Heart Association Call to Action: Obesity as a Major Risk Factor for Coronary Heart Disease

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Authors

RERobert H. EckelRKRonald M. Krauss

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Overview

Scientific statement demonstrates obesity as a major modifiable risk factor for coronary heart disease, highlighting the urgent need for clinical weight-management strategies.

Key Points

  • To reclassify obesity as a major, independent, and modifiable risk factor for coronary heart disease and outline necessary clinical and public health interventions.
  • Expert consensus review evaluating extensive epidemiological, pathophysiological, and clinical evidence connecting excess adiposity with cardiovascular disease.
  • Assessment of obesity's direct pathogenic effects on myocardial function as well as its indirect contributions through intermediate risk factors.
  • Reclassifies obesity from a contributing factor to a major, direct risk factor for coronary heart disease and overall cardiovascular morbidity.
  • Identifies that excess adiposity significantly worsens atherogenic dyslipidemia, insulin resistance, type 2 diabetes mellitus, and systemic hypertension.

Cite This Study

Eckel et al. (1998) studied this question.

synapsesocial.com/papers/6abb2d5ef034cae984216883https://doi.org/10.1161/01.cir.97.21.2099
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