Obstructive sleep apnea (OSA) screening using wearable-compatible signals remains challenging because of signal noise, temporal complexity, and physiological variation among individuals. We propose a multimodal Siamese metric-learning framework that jointly models electrocardiography (ECG) and oxygen saturation (SpO ₂ ) dynamics through a dual-branch encoder and triplet-loss optimization. The architecture integrates a 1D ResNet-18 backbone with bidirectional long short-term memory (BiLSTM)-based temporal fusion to capture complementary physiological patterns. We evaluated the framework using subject-disjoint five-fold cross-validation in a curated cohort from the PSG-Audio dataset. The proposed model achieved an accuracy of 91.03 ± 2.75% , recall of 90.58 ± 4.84% , F1-score of 91.03 ± 2.57% , and AUC of 0.9506 ± 0.0342 . Patient identities were separated across training, validation, and test partitions, and test data were excluded from triplet construction, model selection, and threshold selection. These results support multimodal metric learning as a competitive within-cohort approach but do not establish generalization to external populations or recording systems.
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He et al. (2026) studied this question.
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