Key result
Postoperative atrial fibrillation after coronary artery bypass grafting was significantly associated with increased in-hospital mortality (9.26%, P=0.007), acute renal dysfunction, and longer intensive care unit stay.
Why the study?
Atrial fibrillation is the main postoperative complication after cardiovascular surgery, and its rapid identification is essential to mitigate associated risks.
Does the development of postoperative atrial fibrillation increase the risk of hospital complications in patients undergoing isolated CABG?
Observational (n=3,803)
Yes
Does the development of postoperative atrial fibrillation increase the risk of hospital complications in patients undergoing isolated CABG?
Postoperative atrial fibrillation after isolated CABG is significantly associated with acute renal dysfunction and prolonged intensive care unit stay.
INTRODUCTION: Atrial fibrillation is the main complication in the postoperative period of cardiovascular surgery. Its genesis is multifactorial, so its rapid identification to mitigate the associated risks is essential. OBJECTIVE: To evaluate the incidence of atrial fibrillation in patients undergoing coronary artery bypass grafting (CABG) and its relationship with other complications in our setting. METHODS: This is a multicenter, observational study involving patients undergoing isolated CABG between 2017 and 2019 with data from the Registro Paulista de Cirurgia Cardiovascular (or REPLICCAR II). Variables were prospectively collected in REDCap following the definitions given by version 2.73 of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. Data were collected with prior authorization from the local ethics committee and analyses performed in R software. RESULTS: A total of 3,803 patients were included, of these 605 had postoperative atrial fibrillation (POAF). In order to adjust the groups, propensity score matching was used. Such analyses resulted in 605 patients in each group (without POAF vs. with POAF). Among patients with POAF, the mean age was 67.56 years, with a prevalence of males (73.6%, 445 patients). Patients belonging to the group with POAF had a mortality rate of 9.26% (P=0.007), longer ventilation time (P<0.001), pneumonia (P<0.001), and sepsis (P<0.001). In multiple analysis, acute renal dysfunction (P=0.032) and longer intensive care unit stay (P<0,001) were associated with the presence of POAF. CONCLUSION: POAF in CABG is associated with longer intensive care unit and hospital stay, as well as renal dysfunction, pneumonia, and in-hospital mortality.
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Maia et al. (2024) conducted an observational in Coronary Artery Disease undergoing CABG (n=3,803). Postoperative atrial fibrillation (POAF) vs. Without POAF was evaluated on In-hospital mortality (p=0.007). Postoperative atrial fibrillation after coronary artery bypass grafting was significantly associated with increased in-hospital mortality (9.26%, P=0.007), acute renal dysfunction, and longer intensive care unit stay.
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