Key result
Takotsubo syndrome can feature persistent apical akinesis through four months despite complete symptomatic recovery.
Why the study?
Persistent regional wall motion abnormalities beyond the expected recovery period in Takotsubo syndrome are uncommon and not well characterized.
Case Report (n=1)
This case demonstrates that Takotsubo syndrome can present with atypical delayed recovery of wall motion abnormalities (persistent apical akinesis at four months) and marked troponin elevation despite nonobstructive coronary artery disease.
Takotsubo syndrome (TTS) is typically characterized by transient left ventricular (LV) systolic dysfunction with recovery occurring within days to weeks.Persistent regional wall motion abnormalities beyond the expected recovery period are uncommon.We report the case of a 77-year-old woman who presented with nausea, vomiting, epigastric discomfort, dyspnea, ST-segment depressions, and markedly elevated highsensitivity troponin (9,848 ng/L).Coronary angiography demonstrated nonobstructive coronary artery disease, while echocardiography confirmed TTS with apical akinesis and an LV ejection fraction of 35%.A large hiatal hernia was also identified.Although the patient experienced complete symptomatic recovery and returned to baseline functional status, serial echocardiography demonstrated persistent apical akinesis through four months of follow-up.This case highlights an unusual recovery pattern in TTS and demonstrates that marked troponin elevation can occur despite nonobstructive coronary artery disease.
No takes yet. Share an insight, caveat, or question.
Mishra et al. (2026) conducted a case report in Takotsubo syndrome (n=1). Observation was evaluated on Echocardiographic recovery of wall motion abnormalities. A 77-year-old woman with Takotsubo syndrome and marked troponin elevation demonstrated persistent apical akinesis through four months of follow-up despite complete symptomatic recovery.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: