Key result
Height-indexed, but not BMI-indexed, appendicular muscle mass is linked to higher 2-year mortality in older HF.
Why the study?
The comparative prognostic value of BMI-indexed versus height-indexed appendicular skeletal muscle mass in older patients hospitalized for heart failure was unclear.
Does height-indexed appendicular skeletal muscle mass predict 2-year mortality better than BMI-indexed muscle mass in older patients hospitalized for heart failure?
Does height-indexed appendicular skeletal muscle mass predict 2-year mortality better than BMI-indexed muscle mass in older patients hospitalized for heart failure?
Height-indexed ASMM is a more clinically useful marker than BMI-indexed ASMM for post-discharge risk stratification in older patients with heart failure.
Among older patients hospitalized for heart failure, height-indexed appendicular skeletal muscle mass, but not BMI-indexed appendicular skeletal muscle mass, was associated with higher 2-year mortality. Height-indexed ASMM may therefore be the more clinically useful marker for post-discharge risk stratification.
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Nakade et al. (2026) studied this question. Height-indexed appendicular skeletal muscle mass, but not BMI-indexed mass, was associated with higher 2-year mortality among older patients hospitalized for heart failure.
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