Key result
Native degenerative disease and infective endocarditis are linked to higher risk of mitral prosthesis dehiscence.
Why the study?
Risk factors for mitral valve prosthesis dehiscence necessitating reoperation were not well defined in patients with prosthetic mitral valves.
What are the preoperative risk factors associated with mitral valve prosthesis dehiscence necessitating reoperation?
Cohort (n=999)
What are the preoperative risk factors associated with mitral valve prosthesis dehiscence necessitating reoperation?
p-value: p=0.016 (degenerative disease); 0.0006 (infective endocarditis)
Degenerative disease and infective endocarditis of the native valve are significant risk factors for mitral valve prosthesis dehiscence requiring reoperation, which carries a high mortality rate of 30%.
No takes yet. Share an insight, caveat, or question.
Early reoperations for periprosthetic mitral leak signal high risk tied to status; Level 5 data leave open relevance to contemporary techniques.
Rizzoli et al. (1983) conducted a cohort in Previously implanted prosthetic mitral valves (n=999). Degenerative disease or infective endocarditis of the native valve vs. Other native valve diseases (e.g., rheumatic disease) was evaluated on Dehiscence of the mitral prosthesis necessitating reoperation (p=0.016 (degenerative disease); 0.0006 (infective endocarditis)). Degenerative disease (P=0.016) and infective endocarditis (P=0.0006) of the native valve significantly increased the risk of mitral prosthesis dehiscence necessitating reoperation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: