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March 1, 2004Congestive Heart Failure

C ase R eport . Use of Noninvasive Hemodynamics to Aid Decision Making in the Initiation and Titration of Neurohormonal Agents

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Key result

Impedance cardiography noninvasively guides neurohormonal therapy titration in heart failure.

  • n=3

Why the study?

Concern about hemodynamic tolerance limits initiation and up-titration of neurohormonal agents in heart failure, and appropriate patient selection for nesiritide remains challenging.

Can impedance cardiography aid in the initiation and titration of neurohormonal agents in patients with heart failure?

Comparison

Use of impedance cardiography to guide initiation and titration of neurohormonal agents

Design

Case report

Authors

RSRichard L. SummersJackson Memorial HospitalCPCharles W. ParrottProvidence HospitalCQCheryl QualeProvidence Hospital

Discussion

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Overview

May support cautious up-titration of ACEI and beta blockers in chronic HF despite tolerance concerns; leaves open nesiritide's role in this setting.

Study Design

Type

Case Report (n=3)

Structured PICO

Can impedance cardiography aid in the initiation and titration of neurohormonal agents in patients with heart failure?

P
Population
Three case reports of patients with heart failure.
I
Intervention
Impedance cardiography to guide initiation and titration of neurohormonal agents (ACE inhibitors, beta-blockers, nesiritide)
O
Outcome
Utility of hemodynamic data in the initiation and titration of neurohormonal agents

Noninvasive hemodynamics via impedance cardiography may be a useful tool to guide the initiation and up-titration of neurohormonal therapies in heart failure.

Cite This Study

Summers et al. (2004) conducted a case report in heart failure (n=3). Impedance cardiography was evaluated. Impedance cardiography provided noninvasive hemodynamic data that aided the initiation and titration of neurohormonal agents in three patients with heart failure.

synapsesocial.com/papers/6abe585db297982ddf6e5eb6https://doi.org/10.1111/j.1527-5299.2004.03552.x

Topics

Heart failureHFrEF treatment
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