Ion-channel gene expression in diabetic arterial tissue: a pre-registered cross-species meta-analysis of public transcriptomic datasets with an independent, metadata-selected validation set

This is the authors' abstract. We don't add key points for this paper.

Secondary-data study (P10). Public GEO datasets of intact arterial tissue from diabetic and non-diabetic humans, mice and rats are re-analysed with one pre-specified pipeline to test whether KCNMB1 (BK channel beta-1 subunit) and a pre-specified 19-gene panel of smooth-muscle ion-channel and channel-regulatory genes change in diabetes. No wet-lab data are used.