The Role of Carrot Seed Oil and Pomegranate Seed Oil in Second Degree Burn in Rats: Can All Oils Obtained from Plants Be Used in Burn Treatment?

Objective: Burn is a complex traumatic event that affects many organ systems beyond the skin with various local and systemic effects. As a topical agent to heal a burn wound, one of the most common injuries worldwide, vegetable oils are often used in treatment with their vitamin and antioxidant content. This study was conducted considering that carrot seed oil (CSO) rich in vitamin A and pomegranate seed oils (PSO) rich in omega-5 fatty acid content may be effective in 2nd degree burns in rats.Methods: In the 2nd degree burn model created with brass comb in rats, the wound healing potential of CSO and PSO was studied by randomly dividing 50 wistar albino male rats into 5 groups as healthy, burn control, silverdin control, CSO and PSO. 2nd degree burn pattern was created with brass comb on each animal's back, both right and left. When the day the model was created was accepted as the zero day, the healing percentages were calculated by taking pictures of the burn areas on days 3,7,14 and 21.Results: It was concluded that CSO and PSO, compared with control groups, did not act in a curative direction when recovery percentages and macroscopic examinations were carried out, but rather worsened them.Conclusion: This study demonstrates that contrary to popular belief, not all plant-derived oils are beneficial for burn wound healing.