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October 1, 2026Nature Cardiovascular Research
Refining stress echocardiography reduces the need for invasive testing in heart failure with preserved ejection fraction
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“Exercise stress echocardiography for diagnosis of heart failure with preserved ejection fraction: a multicentre study. Addition of LA strain imaging with optimized rule-in or rule-out values improves diagnostic triage by expanding non-invasive rule-in/rule-out classifications while identifying patients who still require invasive testing in the evaluation of HFpEF.”
AAAbdulla A. DamlujiInterventional cardiologist, Professor of Medicine
“Current guidance starts with a probability score (HFA PEFF, H2FPEF or HFpEF ABA). A high score rules in the diagnosis but a low score rules it out. An intermediate score calls for exercise testing, and guidelines endorse stress echocardiography as an alternative to catheterization.”
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Andrea Tavosanis (2026) studied this question.