Key result
Antihypertensive adherence links to optimal BP control and reduced stroke, HF, and CKD risk.
Why the study?
Effective blood pressure control depends on both pharmacological therapy and patients' adherence to antihypertensive medication, but the role of adherence in preventing complications needed review.
Does adherence to antihypertensive medication improve blood pressure control and prevent complications in patients with hypertension?
Does adherence to antihypertensive medication improve blood pressure control and prevent complications in patients with hypertension?
Medication adherence, supported by continuous health education and collaborative care, is essential for optimal blood pressure control and preventing cardiovascular complications in hypertensive patients.
May warrant adherence support in hypertension care; leaves open causal confirmation from prospective trials.
Hypertension remains one of the leanding non-communicable diaseases contributing to cardiovascular morbidity and mortality worldwide. Effective blood pressure control depends not only on pharmacological therapy but also on patiens adherence to antihypertensi medication. This study aimed to review scientific evidence regarding medication adherence and its role in controlling blood pressure and preventing hypertension-related complications. This study employed a literature review approach by analyzing scientific articles published between 2020 and 2025 from Google Scholar, PubMed, and ScienceDirect databases. The reviewed studies indicate that medication adherence is significantly associated with optimal blood pressure control and reduced risk of complications such as stroke, heart failure, coronary artery disease, and chronic kidney disease. Several factors influencing adherence include patients' knowledge, motivation, family support, healthcare provider support, duration of treatment, and access to healthcare services. Continuous health education and collaborative care among patients, families, and healthcare professionals are essential to improve adherence and optimize hypertension management. Therefore, strengthening patient education and adherence interventions should become an integral part of hypertension management programs.
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Pakpahan et al. (2026) conducted a review in Hypertension. Antihypertensive medication adherence vs. Non-adherence was evaluated on Blood pressure control and risk of complications. Antihypertensive medication adherence is significantly associated with optimal blood pressure control and reduced risk of complications such as stroke, heart failure, and chronic kidney disease.
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