Key result
Early angioplasty resolves severe LAD stenosis and averts infarction in Wellens syndrome.
Why the study?
Wellen’s syndrome is a critical ECG pattern indicating significant proximal LAD stenosis and a pre-infarction state requiring early recognition and intervention to prevent myocardial infarction.
Case Report (n=1)
No
Early recognition of Wellens syndrome ECG patterns is crucial to prompt urgent coronary angiography and revascularization, preventing anterior myocardial infarction.
Case report supports Wellens ECG vigilance in chest pain; leaves open prospective validation before broader adoption.
Wellen’s syndrome is a critical electrocardiographic pattern indicative of significant proximal left anterior descending (LAD) artery stenosis, representing a pre-infarction state. The authors report a 76-year-old hypertensive woman presenting with exertion-induced, non-radiating chest pain. ECG during a pain-free interval showed biphasic T waves in V2–V3 with elevated troponin I. Coronary angiography confirmed 95% LAD stenosis. The patient underwent successful percutaneous coronary intervention (PCI) and was started on dual antiplatelet and statin therapy. Early identification of this ECG pattern is crucial, as stress testing is contraindicated due to the high infarction risk. This case underscores the diagnostic importance of Wellen’s syndrome and the role of early invasive management.
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Satwick et al. (2025) conducted a case report in Wellens syndrome (n=1). Percutaneous transluminal coronary angioplasty (PTCA) was evaluated on Clinical stability and prevention of myocardial infarction. Prompt recognition of Wellens syndrome and early percutaneous transluminal coronary angioplasty successfully treated 95% LAD stenosis and prevented myocardial infarction in a 76-year-old woman.
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