Key result
Masked hypertension, obesity, male sex, and ACE inhibitor/ARB use were independently associated with higher ambulatory arterial stiffness index in children and adolescents with chronic kidney disease.
Why the study?
Does the Ambulatory Arterial Stiffness Index (AASI) serve as a marker for early vascular ageing in children with chronic kidney disease?
Does the Ambulatory Arterial Stiffness Index (AASI) serve as a marker for early vascular ageing in children with chronic kidney disease?
AASI derived from routine 24-hour ABPM may serve as a simple, non-invasive marker to identify early vascular ageing and elevated cardiovascular risk in pediatric CKD patients.
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Sarkar et al. (2026) conducted an editorial in Chronic kidney disease (n=654). Masked hypertension and obesity vs. Normotensive and normal weight children was evaluated on Ambulatory arterial stiffness index (AASI). Masked hypertension, obesity, male sex, and ACE inhibitor/ARB use were independently associated with higher ambulatory arterial stiffness index in children and adolescents with chronic kidney disease.
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