Key result
Elevated HADS score linked to ~3-fold higher rate of new antidepressant initiation.
Why the study?
The impact of incentivised depression screening in chronic disease on routine primary care practice was uncertain.
Population
125,143 primary care patients with coronary heart disease, diabetes, or stroke in Scotland
Comparison
Patients with raised HADS (≥8) vs normal HADS (<8) on antidepressant initiation
Design
Cross-sectional analysis of routinely collected data
Follow-up
6 months
Authors
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May increase antidepressant initiation after positive screens; leaves open whether routine HADS improves outcomes in chronic disease.
Cross-Sectional (n=125,143)
Yes
Relative Risk: 3.3 (95% CI 2.97–3.67)
Absolute Event Rate: 8% vs 2.4%
p-value: p=<0.0001
Jani et al. (2013) conducted a cross-sectional in Chronic disease (coronary heart disease, diabetes, stroke) (n=125,143). Raised Hospital Anxiety and Depression Score (HADS ≥8) vs. Normal HADS (<8) was evaluated on Antidepressant initiation within 6 months (RR 3.3, 95% CI 2.97-3.67, p=<0.0001). A raised Hospital Anxiety and Depression Score (≥8) during routine screening of patients with chronic diseases was associated with a significantly higher rate of new antidepressant initiation (RR 3.3).
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