Key result
Environmental pollution and poor nutrition synergistically drive inflammatory and degenerative cardiovascular changes.
Why the study?
The synergistic effect of environmental pollution and unfavorable nutrition on the pathogenesis of cardiovascular diseases requires clarification to inform prevention strategies.
Highlights the need for an integrative preventive approach combining environmental medicine, nutrition, and cardiology to manage cardiovascular diseases.
Supports integrated environmental-nutritional CVD prevention; leaves open causal validation and intervention trials.
This article examines the relationship and interaction of environmental and nutritional factors in the pathogenesis of cardiovascular diseases (CVD). Based on an analysis of current scientific sources, it emphasizes that environmental pollution (PM2.5, NO₂, heavy metals, organic toxins) and unfavorable nutrition (excess trans fats, salt, antioxidant deficiency) exert a synergistic effect on the development of inflammatory and degenerative changes in the cardiovascular system. Special attention is given to the mechanism of factor interaction, which includes oxidative stress, endothelial dysfunction, and mitochondrial disturbances. The necessity of a comprehensive preventive approach based on improving nutrition quality and reducing environmental risk exposure is justified.
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Farida Azizova (2025) conducted a review in Cardiovascular diseases. Environmental pollution and unfavorable nutrition was evaluated. Environmental pollution and unfavorable nutrition exert a synergistic effect on the development of inflammatory and degenerative changes in the cardiovascular system.
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