Key result
Intensive lifestyle intervention enables antihypertensive discontinuation alongside ~8 kg weight loss in case report.
Why the study?
Although lifestyle factors are recognized as first-line management for hypertension, this knowledge has not fully translated into practice, necessitating behavioural interventions to sustain lifestyle changes.
Can intensive lifestyle modifications and behavioural interventions reverse hypertension and promote weight loss in a patient with hypertension and obesity?
Case Report (n=1)
Can intensive lifestyle modifications and behavioural interventions reverse hypertension and promote weight loss in a patient with hypertension and obesity?
Intensive lifestyle modifications supported by behavioural interventions like MI, CBT, and PP can effectively reverse hypertension and induce significant weight loss.
May support intensive behavioral interventions for select hypertensive patients; hypothesis-generating and leaves open confirmation in controlled trials.
Lifestyle-related factors such as diet, physical activity, stress management, and sleep, among others, are very important in preventing and treating hypertension. These factors have been recognized by the World Health Organization, the Joint National Committee, and other bodies as the first line, with or without medications, in managing hypertension. Although these factors are well known to both patients and medical personnel, this knowledge has not fully translated into the practice of healthy lifestyle choices. Therefore, there is a need for behavioural interventions like motivational interviewing (MI), cognitive behavioural therapy (CBT), and positive psychology (PP) to help an individual effect and sustain a lifestyle change. This case describes a 35-year-old man with hypertension, overweight, truncal obesity, and chronic stress. He was commenced on lifestyle interventions, which included MI, CBT, and PP, to get him to the action phase in the Trans-Theoretical Stage of Change (TTSC). These changes spanned his diet and nutrition, sleep, and physical activity profiles. He was also commenced on S-amlodipine 5mg dose. After seven weeks of intervention, he was taken off the antihypertensive following low blood pressure readings. He also lost 8 kg of weight after 12 weeks with a reduced abdominal circumference. It is concluded that reversal of hypertension is achievable with Intensive Lifestyle Modification. Behavioural interventions like MI, CBT, and PP are essential for developing and sustaining lifestyle modifications.
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Elemile et al. (2025) conducted a case report in Hypertension, overweight, truncal obesity, and chronic stress (n=1). Intensive lifestyle modifications (MI, CBT, PP) and S-amlodipine was evaluated on Blood pressure and weight reduction. Intensive lifestyle modifications including motivational interviewing and cognitive behavioural therapy led to discontinuation of antihypertensive medication at 7 weeks and an 8 kg weight loss at 12 weeks.
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