Key result
Lacunar stroke links to over-dipper BP profiles, while hemorrhagic stroke associates with night-peaker patterns.
Why the study?
The characteristics of 24-hour blood pressure profiles and nighttime sleep in patients with lacunar infarction and hemorrhagic stroke during the acute period were not well characterized.
Cross-Sectional (n=120)
No
p-value: p=≤0.05
Patients with lacunar infarction predominantly exhibit an over-dipper blood pressure profile, whereas those with hemorrhagic stroke more frequently show night-peaker and non-dipper profiles, highlighting the need for individualized antihypertensive therapy based on circadian rhythms.
Lacunar infarction linked to over-dipper and hemorrhagic stroke to night-peaker/non-dipper profiles; leaves open whether rhythm modification alters risk or warrants subtype-specific therapy.
The aim of the present study was to assess the characteristics of the 24-hour blood pressure (BP) profile and nighttime sleep in patients with lacunar infarction (LI) and hemorrhagic stroke (HS). The study included 120 patients who underwent 24-hour BP monitoring (ABPM) and clinical evaluation during the acute period of stroke. We analyzed average 24-hour, daytime, and nighttime systolic (SBP) and diastolic (DBP) values, the 24-hour index, as well as BP circadian rhythm types: dipper, non-dipper, over-dipper, and night-peaker. It was found that the over-dipper type was more frequently observed in patients with LI, whereas in HS patients the night-peaker and non-dipper profiles predominated. The obtained data confirm the pathogenetic role of a disrupted circadian BP rhythm in the development of stroke, particularly during the nighttime period, and highlight the need for an individualized approach to antihypertensive therapy, taking into account circadian features of BP and sleep.
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Ravshan Shukurovich Abdurakhmanov (2025) conducted a cross-sectional in Lacunar infarction and hemorrhagic stroke (n=120). Lacunar infarction vs. Hemorrhagic stroke was evaluated on Circadian blood pressure rhythm types (dipper, non-dipper, over-dipper, night-peaker) (p=≤0.05). Patients with lacunar infarction more frequently exhibited an over-dipper blood pressure profile, whereas those with hemorrhagic stroke predominantly showed night-peaker and non-dipper profiles.
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