Key result
Massive pulmonary embolism can present atypically with generalized seizures as the initial clinical manifestation.
Why the study?
Pulmonary embolism has varied clinical presentations with no specific signs or symptoms, and generalized seizures as an initial presentation are infrequent and rarely reported.
Case Report (n=1)
Massive pulmonary embolism can rarely present with generalized seizures, requiring a high index of suspicion for diagnosis.
Consider PE in unexplained seizures; extends reported neurologic manifestations but leaves open systematic study.
Pulmonary embolism has varied clinical presentations; there are no specific signs and symptoms associated with this disease, so a high level of suspicion is required to diagnose this potentially fatal disease. Although syncope secondary to pulmonary embolism has been reported in the literature, generalized seizures secondary to PE are infrequent, and only a few cases have been reported in the literature. Therefore, we present a case of massive pulmonary embolism with seizures as the initial presentation.
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Sheikh et al. (2022) conducted a case report in Massive pulmonary embolism (n=1). Massive pulmonary embolism was evaluated on Clinical presentation. Massive pulmonary embolism can infrequently present initially with generalized seizures, requiring a high index of clinical suspicion for diagnosis.
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