Rodents treated with extract from Xanthium strumarium Linn. (Compositae) exhibited alterations in general behavior patterns, reduction in spontaneous motility, prolongation of pentobarbitone-induced sleep, suppression of exploratory behavior patterns, and avoidance response. The observations suggested Xanthium strumarium had significant depressant action of the central nervous system.
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Mandal et al. (2001) studied this question.
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