We read with interest the 2 case reports of acute kidney injury (AKI) associated with semaglutide use, described by Leehey et al,1 given the risks associated with AKI.2,3 In light of the reported kidney benefits of glucagon-like peptide-1 receptor agonists (GLP-1RAs),4,5 we investigated whether GLP-1RAs are associated with increased risk for AKI, pooling data from cardiovascular outcome trials that enrolled high- or very-high-risk individuals with type 2 diabetes mellitus.
No takes yet. Share an insight, caveat, or question.
Patoulias et al. (2021) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: