A Comparison of Modern Cardiovascular Parameters in Patients with and Without Blood Stasis Syndrome

Objective: To study the relation between cardiovascular parameters and blood stasis syndrome (BSS) by investigating the conventional cardiovascular parameters of BSS, furthermore, finding out the objective evidence for TCM syndrome differentiation. Methods: A total of 66 patients with a mean age of 60±18 years were evaluated. Out of these, 30 had BSS and 36 did not (control group). All patients underwent an evaluation of brachial mean arterial pressure (MAP), brachial diastolic pressure (DP), brachial systolic pressure (SP), aortic systolic pressure (SP), aortic MAP, and aortic DP in the seated and supine positions using a SphygmoCor XCEL. Pulse wave velocity (PWV), aortic augmentation index (Aix), ejection duration, and heart rate (HR) in the seated and supine positions determining by electrocardiogram examination. Results: There were no significant differences in the age, height, weight, gender, or race (P>0.05) of the two groups. A significant difference was observed in the brachial SP, brachial MAP, brachial DP, aortic SP, aortic MAP, aortic DP, and HR of the two patient groups in the supine position (P<0.05 or P<0.01). Ejection duration and Aix were reduced and PWV examined in the supine position increased in the BS group, compared with the control group, although the differences were not significant (P>0.05). Seated patients with BSS had a lower MAP and aortic MAP than control patients (P<0.05). All other parameters in the two groups examined in the seated position were not significantly different (P>0.05). Conclusion: Changes in modern medical cardiovascular parameters were found in patients with BSS. These preliminary findings may be used to evaluate and treat patients with the disorder. Further controlled studies are needed to confirm these findings.