Key result
SARS-CoV-2 infection causes pediatric cardiovascular injury, driven primarily by inflammation and ACE2 receptor binding.
Why the study?
Children under ten years old constitute about 1% of SARS-CoV-2 infections and can exhibit cardiovascular system damage, but the mechanisms and effects are not fully understood.
May warrant cardiac monitoring in pediatric SARS-CoV-2 cases; leaves open the need for prospective studies to quantify risk.
In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began to break out in the Hubei Province of China. At present, the epidemic situation in the world continues and the number of confirmed cases is increasing every day. A recent review showed that children under the age of ten years make up about 1% of the infected population, which cannot be ignored. Studies have shown that after SARS-CoV-2 infection children can show clinical symptoms of cardiovascular system damage in addition to typical respiratory symptoms. This article mainly discusses the possible damage of SARS-CoV-2 to children's cardiovascular system and related mechanisms.
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Zhang et al. (2020) conducted a review in SARS-CoV-2 infection. SARS-CoV-2 infection was evaluated. SARS-CoV-2 infection can cause cardiovascular system injury in children through mechanisms such as inflammatory responses, ACE-2 receptor binding, hypoxemia, and stress.
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