Key result
SARS-CoV-2 infection causes various cardiovascular manifestations, including acute coronary syndrome, myocarditis, heart failure, and arrhythmias, through direct viral invasion, systemic inflammation, and endothelial dysfunction.
Why the study?
SARS-CoV-2 infection is associated with endothelial dysfunction, inflammation, thrombosis, and microvascular obstruction that can cause myocardial and coronary lesions and clinical cardiovascular manifestations.
SARS-CoV-2 infection can cause significant cardiovascular complications through systemic inflammation, endothelial dysfunction, and microvascular thrombosis.
Clinicians should monitor for cardiovascular complications in SARS-CoV-2 patients; extends prior syntheses but leaves targeted management trials open.
Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 may have a mild presentation, with few symptoms, or progress to a severe condition, characterized by generalized inflammation, systemic microvascular involvement, coagulopathy, and pulmonary and cardiovascular complications. Men present with more severe symptoms than women, especially men who are older and who present with comorbidities such as hypertension, diabetes mellitus, and a history of atherosclerotic diseases. Owing to its association with endothelial dysfunction, inflammation, thrombosis, and microvascular obstruction, SARS-CoV-2 infection can cause lesions in several organs, including the myocardium and the coronary arterial bed, which can result in clinical manifestations involving the cardiovascular system. In this mini review, we summarize the effects of SARS-CoV-2 infection on the cardiovascular system in both children and adults and characterize the various clinical manifestations associated with this disease.
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Yugar‐Toledo et al. (2023) conducted a review in Cardiovascular manifestations of SARS-CoV-2 infection. SARS-CoV-2 infection was evaluated. SARS-CoV-2 infection causes various cardiovascular manifestations, including acute coronary syndrome, myocarditis, heart failure, and arrhythmias, through direct viral invasion, systemic inflammation, and endothelial dysfunction.
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