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November 11, 2020Journal of Molecular Cell BiologyOpen Access

COVID-19 and cardiovascular diseases

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Key result

COVID-19 is associated with diverse clinical complications of the heart and vascular system, potentially driven by systemic inflammation and ACE2-involved signaling networking.

Why the study?

COVID-19 has severe implications in the cardiovascular system, requiring an integration of clinical observations and experimental findings to understand underlying mechanisms and aid in identifying and treating cardiovascular injury.

Design

Review

Authors

FLFan LiuXuzhou Medical CollegeFLFeng LiuWeifang Medical UniversityLWLu WangSun Yat-sen University

Discussion

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Member takes

Overview

May warrant vigilance for cardiovascular complications in COVID-19; leaves open causal roles of inflammation and ACE2 for prospective confirmation.

Structured PICO

P
Population
Patients with COVID-19
O
Outcome
Cardiovascular complications and mortality

This review highlights the diverse cardiovascular complications of COVID-19 and the potential underlying mechanisms involving systemic inflammation and ACE2 signaling.

Cite This Study

Liu et al. (2020) conducted a review in COVID-19 and cardiovascular diseases. COVID-19 was evaluated. COVID-19 is associated with diverse clinical complications of the heart and vascular system, potentially driven by systemic inflammation and ACE2-involved signaling networking.

synapsesocial.com/papers/6a2304e96873956e4bd26dbdhttps://doi.org/10.1093/jmcb/mjaa064
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Guidance for Cardiac Electrophysiology During the COVID-19 Pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association2020 · 135 citations
  2. 2Cytokine-Induced Modulation of Cardiac Function2004 · 379 citations
  3. 3ACE2/Ang-(1–7) signaling and vascular remodeling2014 · 61 citations
  4. 4Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 22005 · 1,618 citations
  5. 5Reduced Endothelial NO-cGMP–Mediated Vascular Relaxation and Hypertension in IL-6–Infused Pregnant Rats2004 · 91 citations