Key result
Lower admission serum calcium is linked to ~49% lower sudden cardiac arrest risk per unit increase.
Why the study?
The association of serum calcium with sudden cardiac arrest in patients with acute stroke was not well established.
Observational (n=10,226)
Yes
Answers are grounded in this paper and cite their sources.
Serum calcium may associate with post-stroke SCA; hypothesis-generating and should not yet change practice.
The aim of our study was to investigate the association of serum calcium with sudden cardiac arrest (SCA) in patients with stroke. We evaluated the clinical data of 10226 acute stroke patients admitted to the intensive care unit. We assessed the correlation between serum calcium and SCA after acute stroke by multivariate logistic regression. A nonlinear association between platelet count and mortality of HS patients was investigated using a generalized additive model and smooth curve fitting. In this study, we found lower Serum Calcium at admission was associated with SCA of almost two times as high as that for that non-low calcium patients. An increment of per unit in serum calcium was associated with a 49% decrease in SCA. We found that the link between serum calcium at admission and SCA after stroke in the hospital was likewise nonlinear. In addition, we demonstrated that the inflection point of the serum calcium was 8.7 mg/dL. This study demonstrates a nonlinear relationship between serum calcium and the risk of SCA after stroke. Low serum calcium was a risk factor associated with in-hospital SCA after stroke, and elevated serum calcium may be a great intervention for decreasing the incidence of SCA after stroke.
No takes yet. Share an insight, caveat, or question.
Hou et al. (2023) conducted an observational in Acute stroke (n=10,226). Serum calcium vs. Non-low serum calcium was evaluated on Sudden cardiac arrest (SCA) (49% decrease per unit increment). Lower serum calcium at admission was associated with an almost two-fold higher risk of sudden cardiac arrest in acute stroke patients, with a 49% decrease in risk per unit increment.