Key result
BAN-ADHF score predicts poor 24-hour diuretic efficiency in critically ill ADHF with ~0.78 AUROC.
Why the study?
Prior validations of the BAN-ADHF score excluded critically ill patients with acute decompensated heart failure, leaving its performance in this population uncertain.
Does the BAN-ADHF score predict diuretic efficiency in critically ill adults with acute decompensated heart failure?
Cohort (n=1,505)
No
Does the BAN-ADHF score predict diuretic efficiency in critically ill adults with acute decompensated heart failure?
The BAN-ADHF score successfully identifies critically ill heart failure patients at risk for poor diuretic response, highlighting those who may need closer monitoring or alternative decongestive strategies.
May identify low-efficiency patients for monitoring in ICU ADHF; extends prior validations but leaves practice change open pending trials.
In a critically ill cohort of 1505 patients with acute decompensated heart failure, the BAN-ADHF score was inversely associated with diuretic efficiency (Spearman ρ = -0.518) and discriminated the lowest-efficiency quintile (AUROC 0.780 at 24 h; 0.769 at 72 h), with efficiency falling more than four-fold across risk categories. This first external validation in an intensive-care population extends the evidence for BAN-ADHF to patients excluded from prior cohorts and supports prospective evaluation of score-guided decongestive strategies in critical illness.
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Otabor et al. (2026) conducted a cohort in Acute decompensated heart failure in critical illness (n=1,505). BAN-ADHF score vs. Lower BAN-ADHF score categories was evaluated on Lowest diuretic-efficiency quintile at 24 hours (AUROC 0.780, 95% CI 0.743-0.812). The BAN-ADHF score was inversely associated with diuretic efficiency and discriminated the lowest-efficiency quintile with an AUROC of 0.780 at 24 hours in critically ill patients with acute decompensated heart failure.
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