Key result
PTCA is associated with significantly reduced QT and QTc dispersion at 24 hours post-procedure.
Why the study?
QT dispersion increases in myocardial ischemia and is reported to reduce after reperfusion treatment, but the effects of angioplasty on QT and JT dispersion need evaluation.
Observational (n=72)
Answers are grounded in this paper and cite their sources.
QTd reduction post-angioplasty may indicate reperfusion success; leaves open its clinical utility as a marker pending larger prospective studies.
Background：QT dispersion, reflecting inhomogenous ventricular repolarization, increases in myocardial ischemia.In addition, Many studies reported that prolonged QT dispersion reduced to normal after reperfusion treatment.We have carried out this study to evaluate the QT and JT dispersion before and after the angioplasty in patients with coronary artery diseases.Method and Materials：Seventy-two patients (55 men and 17 women： 18 acute myocardial infarction, 9 unstable angina and 45 stable angina) who underwent percutaneous transluminal coronary angioplasty were evaluated.Standard 12-lead electrocardiograms were recorded 24 hours before and 24 hours after angioplasty at a paper speed of 25 mm/sec.Results：There was no significant change in heart rate or the maximum or minimum QT interval after angioplasty.QT dispersion significantly decreased after angioplasty (p<0.05).And QTc dispersion (QTcd) also similary reduced (p<0.01).JT dispersion (JTc) and JTc dispersion (JTcd) were not changed significantly.There were significant reduction in QTd and QTcd in the group of patients without acute myocardial infarction (p＝0.005,0.004, respectively) but not in JTd and JTcd.However, in patients with acute myocardial infarction, all four dispersion were not reduced significantly.And in patients with multivessel angioplasty, there were significant reduction of QTd, QTcd, JTd and JTcd (p＝0.016,0.014, 0.036, 0.030, respectively).Conclusions：As changes in QT and JT dispersion reflect successful reperfusion by angioplasty, they can be accepted as promising test for assessing the effectiveness of angioplasty clinically.However the methodology still has several unresolved issues and larger, prospective clinical studies are needed.( ( ( (Korean Circulation J 1998 ; 28( ( ( (8) ) ) ) : 1280-1286) ) ) ) KEY WORDS：Angioplasty•QT dispersion•JT dispersion.서 론 QT간격은 심실의 활동전위기간을 반영하는 것 1) 으로 심근허혈시 전기생리학적인 변화가 일부 심근에만 국 한되어 있으므로 허혈심근이 위치한 표면심전도유도에 서 QT간격이 연장될수 있고, 이로인해 12유도 심전도 상 각 유도 QT간격의 최고치와 최저치의 차이, 즉 QT 분산이 증가하게 된다.2-4) 이렇게 증가된 QT분산은 심근허혈외에도 심근경색증, 5)6) 악성 심실부정맥, 7) 심 부전, 8) 심실비후 9) 등에서도 나타난다.특히
No takes yet. Share an insight, caveat, or question.
Kim et al. (1998) conducted an observational in Coronary artery diseases (n=72). Percutaneous transluminal coronary angioplasty vs. Baseline (24 hours before angioplasty) was evaluated on QT dispersion (p=<0.05). Percutaneous transluminal coronary angioplasty significantly decreased QT dispersion (p<0.05) and QTc dispersion (p<0.01) at 24 hours post-procedure.
Synapse has enriched 10 related papers. Consider them for comparative context: