Key result
Early hospital activity-based retraining fails to significantly improve functional performance after stroke.
Why the study?
The effectiveness of early, activity-based retraining of activities of daily living after stroke is not clear.
Does early hospital-based activity-based retraining improve functional performance in adults following a stroke?
Meta-Analysis (n=254)
Does early hospital-based activity-based retraining improve functional performance in adults following a stroke?
Standardized Mean Difference: 0.41 (95% CI -0.06–0.87)
p-value: p=0.09
Early activity-based retraining targeting activities of daily living in the hospital setting did not yield a statistically significant improvement in functional performance for stroke patients.
INTRODUCTION: Early after stroke, inpatients commonly experience difficulty performing activities of daily living (ADL). Occupational therapists are key to providing early rehabilitation to optimise recovery. However, the effectiveness of early, activity-based retraining of ADLs is not clear. The aim of this systematic scoping review is to determine whether activity-based retraining targeting basic activities of daily living (b-ADL) and/or simple cognitive instrumental activities of daily living (C-IADL) delivered early after stroke improves functional independence. METHODS: MEDLINE, CINAHL, and Embase were searched. Eligible studies included randomised controlled trials or quasi-randomised trials, with at least 75% of participants over the age of 18, with a stroke diagnosis, and who received activity-based interventions within the hospital setting. Articles were screened by two authors using Covidence. Risk of bias was assessed using Cochrane's Risk of Bias tool (RoB2). All results were meta-analysed using Comprehensive Meta Analysis software (V4.0). CONSUMER AND COMMUNITY INVOLVEMENT: No consumer or community involvement was included in this study. RESULTS: A total of 7546 articles were screened, and six studies including n = 254 participants met the inclusion criteria. Performance outcome measure results were meta-analysed; there was no statistically significant impact of activity-based interventions on functional performance (standardised mean difference [SMD] = 0.41; 95% confidence interval [CI] -0.06, 0.87; P = 0.09). Two studies reviewed quality of life and satisfaction outcomes; data were not synthesised. CONCLUSION: Whereas individual trials suggested improvements early after activity-based training, our meta-analysis showed variability in effects in trials to date. Further research is required to determine the clinical and cost-effectiveness of activity-based interventions within the hospital setting to guide occupational therapy practice.
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Grant et al. (2026) conducted a meta-analysis in Stroke (n=254). Activity-based interventions targeting activities of daily living was evaluated on Functional performance (SMD 0.41, 95% CI -0.06, 0.87, p=0.09). Early hospital-based activity-based interventions did not significantly improve functional performance in post-stroke patients (SMD 0.41; 95% CI -0.06, 0.87; P=0.09).
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