Key result
Low-energy internal cardioversion restores sinus rhythm in ~92% of persistent AF patients.
Why the study?
Low energy internal cardioversion is effective for atrial fibrillation refractory to external cardioversion but is invasive and requires fluoroscopy, motivating assessment of a simplified procedure.
May offer an alternative for persistent AF cardioversion; leaves open the need for randomized confirmation of safety and efficacy.
BACKGROUND: Low energy internal cardioversion is a safe and effective procedure to restore sinus rhythm in patients with atrial fibrillation refractory to external cardioversion. However the procedure is invasive and fluoroscopy is mandatory. Aim of the study To assess the efficacy, safety and tolerability of a new simplified procedure of low energy internal cardioversion. METHODS: Twenty-five consecutive patients (19 males and 6 females) with persistent atrial fibrillation were submitted to low energy internal cardioversion using a step-up protocol (in steps of 50 V, starting from 300 V). A large surface area lead (cathode) was positioned in the oesophagus, 45 cm from the nasal orifice. A second large surface area lead (anode) was positioned in the right atrium. A quadripolar lead was positioned at the right ventricular apex to achieve ventricular synchronization and back-up pacing. Oesophageal endoscopy was performed within 24 h of the end of the procedure and repeated after 48 h, if injury to the oesophageal mucosa had occurred. RESULTS: Sinus rhythm was restored in 23 patients (92%) with a mean delivered energy of 15.74 J (range 5-27) and a mean impedance of 48 Omega. In two patients, endoscopy revealed that small burns had occurred in the oesophageal mucosa. Such lesions spontaneously healed after 48 h. CONCLUSIONS: This new technique of performing low energy internal cardioversion is effective and safe and avoids the positioning of a lead in the coronary sinus or in the left pulmonary artery, thereby simplifying the procedure.
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Massimo Santini (2000) studied persistent atrial fibrillation (n=25). Low energy internal cardioversion with oesophageal-right atrial lead configuration was evaluated on Restoration of sinus rhythm. Low energy internal cardioversion using an oesophageal-right atrial lead configuration successfully restored sinus rhythm in 92% of patients with persistent atrial fibrillation.
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