Key result
Delayed diagnosis and poor therapeutic compliance were significantly associated with non-recovery of myocardial function at 12 months in women with peripartum cardiomyopathy.
Why the study?
Peripartum cardiomyopathy is a severe and frequent disease in women of childbearing age with uncertain long-term myocardial function recovery factors.
Cohort (n=60)
Yes
Effect estimate: Coefficient -0.36 (95% CI -0.57; -0.15)
p-value: p=0.001
May warrant emphasis on prompt diagnosis and adherence in peripartum cardiomyopathy; leaves open causal impact and optimal interventions.
Peripartum cardiomyopathy is one of the curable cardiomyopathy. It’s a severe and frequent disease arising among women of childbearing age. Its evolution in the long-term among some patients leads to chronic heart failure. Our study aims to determine from a prospective cohort, the factors associated with the non-recovery of myocardial function upon 12 months of diagnosis. Sociodemographic, clinical and echocardiographic data were collected at the time of diagnosis and then in months 3, 6 and 12. The outcome was the non-recovery of myocardial function at one year, defined by a left ventricular ejection fraction (LVEF) below 50%. 60 patients were analyzed after 12 months of follow-up. Mortality was about 13.3% and recovery rate of myocardial function reached 42.3%. After logistic regression, delay diagnosis and observance were the factors related to non- recovery of myocardial function.
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Seghda et al. (2020) conducted a cohort in Peripartum cardiomyopathy (n=60). Therapeutic compliance vs. Poor compliance was evaluated on Non-recovery of myocardial function at one year (LVEF < 50%) (Coefficient -0.36, 95% CI -0.57; -0.15, p=0.001). Delayed diagnosis and poor therapeutic compliance were significantly associated with non-recovery of myocardial function at 12 months in women with peripartum cardiomyopathy.
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