Key result
Stress-induced VPCs in repaired Tetralogy of Fallot are linked to older age at testing.
Why the study?
Late arrhythmia and exercise performance after intracardiac repair of tetralogy of Fallot require evaluation to understand long-term patient outcomes.
Cross-Sectional (n=50)
May signal progressive arrhythmia substrate after TOF repair; hypothesis-generating for arrhythmia surveillance timing.
Treadmill exercise test and cold water face-immersion test were performed in 50 patients with tetralogy of Fallot at a mean age of 11.9 years, an average of 8.2 years after intracardiac repair. Cardiac catheterization was also performed in 45 patients 0.5-11 years after the repair.Exercise performance and results of catheterization were compared in patients with and without ventricular premature contraction (VPC) . In 22 (44%) of the 50 patients, VPC was induced by treadmill and/or cold water face-immersion test. Compared with the other 28 patients, the patients who had VPC during the tests, 1) were older (13.6 versus 10.6 years, p< 0.05, t-test) and were tested at a longer interval after repair of tetralogy of Fallot (9.5 versus 7.3 years, p<0.05), 2) showed no difference in the results of catheterization, and 3) had lower exercise performance.Cold water face-immersion test is therefore considered to be useful for evaluation of patients after intracardiac repair of tetralogy of Fallot.
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Komiyama et al. (1990) conducted a cross-sectional in Tetralogy of Fallot after intracardiac repair (n=50). Ventricular premature contraction (VPC) during stress tests vs. No VPC during stress tests was evaluated on Age at testing (years) (p=<0.05). Tetralogy of Fallot patients with stress-induced ventricular premature contractions were older (13.6 vs 10.6 years, p<0.05) and had a longer interval since repair (9.5 vs 7.3 years, p<0.05).
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