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October 1, 1976CirculationOpen Access

Response to exercise in patients after total surgical correction of Tetralogy of Fallot.

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Why the study?

Does upright bicycle exercise reveal impaired cardiovascular function or arrhythmias in asymptomatic patients after total surgical correction of Tetralogy of Fallot compared to normal controls?

Population

43 asymptomatic patients, aged 7 to 41 years, 1 to 14 years after total surgical correction of tetralogy of…

Comparison

Upright bicycle exercise testing vs Normal subjects undergoing the same exercise…

Design

Cross-sectional

Authors

FJFrederick W. JamesTulane UniversitySKSamuel KaplanUniversity of California, Santa CruzDSDavid C. SchwartzUniversity of Wisconsin–Madison

Discussion

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Implication

May support exercise testing for arrhythmia detection in asymptomatic corrected ToF; leaves open prognostic impact and need for prospective validation.

Structured PICO

Does upright bicycle exercise reveal impaired cardiovascular function or arrhythmias in asymptomatic patients after total surgical correction of Tetralogy of Fallot compared to normal controls?

P
Population
43 asymptomatic patients, aged 7 to 41 years, 1 to 14 years after total surgical correction of tetralogy of Fallot (TF), and 109 normal subjects aged 5 to 42 years serving as controls.
I
Intervention
Upright bicycle exercise testing
C
Comparator
Normal subjects (controls) undergoing the same exercise testing
O
Outcome
Heart rate, blood pressure, physical working capacity, and electrocardiographic changes during exercisesurrogate

Exercise testing in asymptomatic patients after Tetralogy of Fallot correction reveals persistent cardiovascular impairment and a significant risk of exercise-induced arrhythmias, highlighting the utility of exercise monitoring in this population.

Cite This Study

James et al. (1976) studied this question.

synapsesocial.com/papers/6a736cdd8412e8bdfca72845https://doi.org/10.1161/01.cir.54.4.671
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sudden death among postoperative patients with tetralogy of Fallot: a follow-up study of 243 patients for an average of twelve years.1976 · 180 citations
  2. 2Arterial Baroreceptor Activity in Rabbits with Experimental Atherosclerosis1974 · 107 citations