Key result
Histologic analysis identifies ganglionic cells and nerve plexuses, defining the sinoatrial node as a neuromuscular organ.
Why the study?
The histological composition of the sino-auricular node, including its nerve fiber and ganglionic cell content, was not fully characterized.
Key points are not available for this paper at this time.
Design
Histological observational study
Answers are grounded in this paper and cite their sources.
SA node harbors intrinsic ganglionic cells and nerve plexuses; leaves open their functional role in sinus node regulation.
Aside from the nerve fibers which enter the pace-making node from the subepicardium, there were observed within the limits of the node a few ganglionic cells and a plexus of moniliform nerve fibrils in very close relation to its muscle fibers, hence the sino-auricular node, like the auriculo-ventricular, may be considered from a histological standpoint a neuromuscular organ.
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Oppenheimer et al. (1912) studied this question. The sino-auricular node contains ganglionic cells and a plexus of moniliform nerve fibrils closely related to its muscle fibers, characterizing it histologically as a neuromuscular organ.
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