Key result
Laser Doppler velocimetry and videomicroscopy characterize dynamic intramyocardial venular blood flow during the cardiac cycle.
Why the study?
The coronary venous system provides a model to investigate the relationship between cardiac contraction and intramyocardial hemodynamics, which requires detailed investigation of coronary venous flow velocity.
Device enables venular diameter and flow observations in beating hearts; leaves open clinical translation to human intramyocardial hemodynamics.
Since coronary venous flow is squeezed out from the myocardial vascular bed by the extravascular compressive force of heart muscle, the coronary venous system provides a suitable model to investigate the relationship between cardiac contraction and intramyocardial hemodynamics. To investigate coronary venous flow velocity in more detail, we previously developed a laser Doppler velocimeter (LDV) with an optical fiber. Furthermore, we have recently developed a needle probe charge-coupled device (CCD) videomicroscope to visualize intramyocardial microvessels. In this article, we report I) blood flow velocity waveforms in the epicardial small veins of the left ventricle and 2) subendocardial venular diameter changes during a cardiac cycle.
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Kajiya et al. (1997) studied Intramyocardial hemodynamics. Laser Doppler velocimeter and CCD videomicroscope was evaluated on Blood flow velocity waveforms in epicardial small veins and subendocardial venular diameter changes.
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