Is Lung Cancer Screening Reaching the People Who Are Most Likely to Benefit?

Lung cancer remains the leading cause of cancer death in the US, largely because most patients have advanced, incurable disease at the time of diagnosis.Lung cancer screening with low-dose computed tomography (LDCT) therefore has the potential to improve lung cancer outcomes through early detection.In 2013, the US Preventive Services Task Force (USPSTF) recommended lung cancer screening with LDCT annually for adults aged 55 to 80 years who have a smoking history of 30 packyears or more, and who currently smoke or formerly smoked but quit within the past 15 years. 1 This recommendation was primarily informed by the results of the National Lung Screening Trial, which demonstrated a 20% reduction in lung cancer mortality among participants aged 55 to 74 years, who underwent 3 rounds of annual screening with LDCT vs chest radiograph. 2 In March 2021, the USPSTF