Key result
Severe hypertension and hyperglycemia are linked to ~2- to 4-fold higher cardiovascular mortality.
Why the study?
Ethnic differences in blood pressure, blood glucose, and their relation to all-cause, cardiovascular, and cerebrovascular mortality in Trinidadian men were not well characterized.
Population
1342 Trinidadian men aged 35 to 69 years
Comparison
Ethnic groups (African descent, Indian, Mixed origin, European) and levels of systolic blood pressure and fasting blood glucose
Design
Prospective cohort survey
Authors
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Supports risk stratification for severe hypertension and hyperglycemia; extends observational data but leaves causal effects and intervention benefits open.
Cohort (n=1,342)
Effect estimate: RR ~2 for all-cause and ~3 for CV mortality (SBP ≥180 vs <130); RR ~4 for all-cause and CV mortality (glucose >7.7 vs 4.2-4.6)
Miller et al. (1988) reported a cohort. Elevated systolic blood pressure and fasting blood glucose vs. Lower systolic blood pressure (<130 mmHg) and fasting blood glucose (4.2-4.6 mmol/l) was evaluated on All-cause, cardiovascular and cerebrovascular mortality (RR ~2 for all-cause and ~3 for CV mortality (SBP ≥180 vs <130); RR ~4 for all-cause and CV mortality (glucose >7.7 vs 4.2-4.6)). Systolic blood pressure ≥180 mmHg and fasting blood glucose >7.7 mmol/l were associated with approximately 2- to 4-fold higher risks of all-cause and cardiovascular mortality.
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