Incidence and predictors of coronary obstruction following transcatheter aortic valve implantation in the real world

Figures

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  Fig. 1.. Flowchart of the included studies. RCT, randomized controlled trial; PSM, propensity score-matching; BEV, balloon-expandable valve; SEV, self-expandable valve.

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  Fig. 2.. Meta-analysis comparing SEVs and BEVs for the intraoperative CO incidence. CO, coronary occlusion.

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  Fig. 3.. Network diagram of the included studies based on the mechanisms of AVR implantation. The thickness of the lines is directly proportional to the number of studies available for each direct comparison. a, BEVs; b, SEVs; c, SAVR. AVR, aortic valve replacement; SAVR, surgical aortic valve replacement.

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  Fig. 4.. A league table of the network comparison among the three implantation mechanisms: BEV, SEV, and SAVR. Green blocks represent a positive effect; red blocks represent a negative effect; the diagonal elements of the league table,the blue squares, indicate comparisons between identical interventions.

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  Fig. 5.. Ranking sort chart for the three implantation mechanisms: BEV, SEV, and SAVR. The x-axis labels correspond to distinct intervention groups (a, BEVs; b, SEVs; c, SAVR). For each intervention, the three bars (left to right in different colors) indicate the probability of ranking first, second, and third for CO incidence among all interventions, with probabilities quantified on the y-axis.

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  Fig. 6.. Network diagram of the included studies based on the AVR implantation valves. (1) Nodes: Each letter (A, B, C…) represents an intervention (A, SAPIEN; B, SAPIEN XT; C, SAPIEN 3; D, CoreValve; E, CoreValve Evolut R; F, CoreValve Evolut PRO; G, ACURATE neo; H, SAVR valves). (2) Edges: line width corresponds to the number of direct clinical trial comparisons.

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  Fig. 7.. A league table of the network comparison among the eight implantation valves: A, SAPIEN; B, SAPIEN XT; C, SAPIEN 3; D, CoreValve; E, CoreValve Evolut R; F, CoreValve Evolut PRO; G, ACURATE neo; and H, SAVR. Green blocks depict a significantly higher CO incidence than the control; red blocks represent a significantly lower CO incidence than the control. Lighter colors indicate smaller effect sizes. The diagonal elements of the league table,the blue squares, indicate comparisons between identical interventions.

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  Fig. 8.. Ranking sort chart for different valves used in AVR implantation. The x-axis labels correspond to distinct intervention groups (A, SAPIEN; B, SAPIEN XT; C, SAPIEN 3; D, CoreValve; E, CoreValve Evolut R; F, CoreValve Evolut PRO; G, ACURATE neo; H, SAVR valves). For each intervention, the bars (left to right in different colors) indicate the probability of being ranked 1st to 8th for CO incidence among all interventions, with probabilities quantified on the y-axis.