Key result
Pulmonary resection is linked to increased plasma proBNP levels peaking at 72 hours.
Why the study?
The detection and clinical relevance of inflammatory reaction and right ventricular dysfunction after pulmonary resection have not been sufficiently evaluated using biomarkers and echocardiography.
Observational (n=38)
Single-blind
No
p-value: p=<0.001
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Post-resection proBNP rise and limited RV changes should not alter practice; leaves open prospective validation for perioperative risk stratification.
Andaluz‐Ojeda et al. (2011) conducted an observational in Pulmonary Resection Surgery (n=38). Pulmonary resection surgery (Pneumonectomy vs Lobectomy) vs. Baseline (preoperative) was evaluated on Plasma proBNP levels at 72 hours post-surgery compared to baseline (p=<0.001). Plasma proBNP levels significantly increased after uncomplicated pulmonary resection surgery, peaking at 72 hours (p < 0.001) regardless of resection extent, while right ventricular function slightly decreased only in pneumonectomy patients.
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