Why the study?
Delayed-enhancement magnetic resonance imaging has been demonstrated to accurately identify myocardial scarring and predict functional recovery after revascularization, but its ability to assess viability as a continuum needed clarification.
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Delayed-enhancement magnetic resonance imaging is a viability imaging technique that has been demonstrated in both animal and patient studies to accurately identify and characterize the presence and transmural extent of myocardial scarring. The precise information regarding the presence, location and extent of myocardial scarring has been shown to be useful in predicting the likelihood of functional recovery of dysfunctional myocardium after revascularization. Perhaps, more importantly, the ability to visualize the extent of viable and nonviable myocardium across the ventricular wall allows one to approach viability as a continuum rather than in a binary manner, providing a better reflection of the underlying physiology.
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Elliott et al. (2005) studied Myocardial viability assessment (n=23). Averaging Morph with Edge Detection (AiM-ED) image registration vs. Traditional nonrigid image registration (NRIR) and other deep learning methods was evaluated on Expert reader scoring of overall image quality (1-5 scale).
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