Key result
Six-month CPAP restores nocturnal blood pressure dipping in severe OSA with resistant hypertension.
Why the study?
Does 6-month continuous positive airway pressure (CPAP) therapy improve ambulatory blood pressure and nocturnal dipping status in Japanese patients with severe obstructive sleep apnea and resistant hypertension?
Case Report (n=3)
No
Does 6-month continuous positive airway pressure (CPAP) therapy improve ambulatory blood pressure and nocturnal dipping status in Japanese patients with severe obstructive sleep apnea and resistant hypertension?
Answers are grounded in this paper and cite their sources.
Six months of CPAP therapy converted nocturnal blood pressure patterns from non-dipper to dipper in two of three non-obese Japanese patients with severe OSA and resistant hypertension, including one with ischemic cardiomyopathy.
The following three case reports present the effects of 6-month continuous positive airway pressure (CPAP) therapy on blood pressure (BP) in severe obstructive sleep apnea patients with resistant hypertension. Case 1 A 58-year-old woman exhibited a decreased 24-hour BP and changes in the nocturnal BP dipping pattern from non-dipper to dipper. Case 2 A 64-year-old man showed no improvements in nocturnal BP. Case 3 A 78-year-old man with ischemic cardiomyopathy exhibited changes in the nocturnal BP dipping pattern from non-dipper to dipper. These results suggest that 6-month CPAP therapy improves the nocturnal BP dipping status in some patients with obstructive sleep apnea and resistant hypertension.
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Sekizuka et al. (2013) conducted a case report in Severe obstructive sleep apnea and resistant hypertension (n=3). Continuous positive airway pressure (CPAP) therapy was evaluated on 24-hour ambulatory blood pressure and nocturnal blood pressure dipping status at 6 months. Six-month CPAP therapy improved nocturnal blood pressure dipping status from non-dipper to dipper in 2 of 3 Japanese patients with severe obstructive sleep apnea and resistant hypertension.
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